Exhaled nitric oxide

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Exhaled Nitric Oxide

Exhaled Nitric Oxide (eNO), pronounced as /ɪkˈsæld ˈnaɪtrɪk ˈɔksaɪd/, is a non-invasive measure of airway inflammation that can be used to help diagnose and manage asthma. The term is derived from the Latin words "exhalare" meaning "to breathe out" and "nitricus" meaning "of or containing nitrogen", and "oxide" from the Greek word "oxys" meaning "sharp, acid".

Definition

Exhaled Nitric Oxide is a gas produced by the body and is present in the exhaled breath. It is produced by the endothelial cells lining the airways and is a marker of inflammation in the lungs. High levels of eNO can indicate uncontrolled asthma or other inflammatory lung conditions.

Measurement

The measurement of eNO is performed using a device called a nitric oxide analyzer. The patient breathes into the device, and the level of nitric oxide in the exhaled air is measured. This measurement can help healthcare providers determine the level of inflammation in the lungs and guide treatment decisions.

Clinical Significance

Exhaled Nitric Oxide testing is used in the diagnosis and management of asthma and other inflammatory lung diseases. It can help to identify patients who may benefit from inhaled corticosteroids, and can also be used to monitor response to treatment. High levels of eNO can indicate poor control of asthma or non-adherence to treatment.

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