Erythropoietin in neuroprotection

Erythropoietin in Neuroprotection

Erythropoietin (pronunciation: /ɪˌrɪθroʊpoʊˈɪtɪn/), often abbreviated as EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine (protein signaling molecule) for erythrocyte (red blood cell) precursors in the bone marrow.

Etymology

The term "Erythropoietin" derives from the Greek words "erythros" meaning "red", "poiesis" meaning "making", and "–in" a common suffix for proteins.

Role in Neuroprotection

Erythropoietin has been found to have neuroprotective effects in the central nervous system. It is involved in neuroprotection, neurogenesis, and angiogenesis, which can help in the recovery of neural function after injury or disease. Neuroprotection refers to the relative preservation of neuronal structure and/or function. In the case of an ongoing insult (a neurodegenerative insult), the relative preservation of neuronal integrity implies a reduction in the rate of neuronal loss over time.

Related Terms

• Cytokine
• Erythropoiesis
• Neuroprotection
• Neurogenesis
• Angiogenesis

See Also

• Neuroprotective Agents
• Erythropoietin Receptor
• Erythropoietin Stimulating Agents

External links

• Medical encyclopedia article on Erythropoietin in neuroprotection
• Wikipedia's article - Erythropoietin in neuroprotection

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