Eprazinone
Eprazinone (also known as Eftapan) is a mucolytic and bronchodilator. It is used in the treatment of respiratory disorders associated with viscid or excessive mucus.
Pharmacology
Eprazinone has both bronchodilator and mucolytic effects. It works by breaking down the structure of mucus in the lungs and therefore facilitating expectoration. It also relaxes bronchial muscles, which helps to reduce bronchospasm and increase airflow to the lungs.
Clinical Use
Eprazinone is used in the treatment of various respiratory disorders where there is excessive mucus production and viscosity. These conditions include chronic bronchitis, asthma, and bronchiectasis. It is also used in the management of cystic fibrosis, a genetic disorder that causes severe damage to the lungs and digestive system.
Side Effects
Like all medications, Eprazinone can cause side effects, although not everybody gets them. Common side effects include gastrointestinal disorders such as nausea, vomiting, and abdominal pain. Less common side effects include allergic reactions, skin rash, and dizziness.
Contraindications
Eprazinone is contraindicated in patients with a known hypersensitivity to the drug or any of its components. It is also contraindicated in patients with severe liver or kidney disease.
Interactions
Eprazinone may interact with other medications, which can affect how it works or increase the risk of side effects. These include other bronchodilators, mucolytics, and certain types of antibiotics.
See Also
- Mucolytic
- Bronchodilator
- Respiratory disorders
- Chronic bronchitis
- Asthma
- Bronchiectasis
- Cystic fibrosis
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Contributors: Prab R. Tumpati, MD