Epigenetics of cocaine addiction

Epigenetics of Cocaine Addiction

Epigenetics of Cocaine Addiction refers to the study of heritable changes in gene expression that do not involve changes to the underlying DNA sequence. This field of study is a significant aspect of Addiction Medicine and Neuroscience, particularly in understanding the molecular and cellular mechanisms of Cocaine Addiction.

Pronunciation

Epigenetics: /ˌepiˈjenətiks/
Cocaine: /kəʊˈkeɪn/
Addiction: /əˈdɪkʃ(ə)n/

Etymology

Epigenetics: Derived from the Greek prefix epi- (ἐπι- "over, outside of, around") and the word genetics (from genesis originally in Greek γένεσις meaning "origin"), implying features that are "on top of" or "in addition to" the traditional genetic basis for inheritance.
Cocaine: From the Spanish coca (from Quechua kuka) + -ine, from Latin -ina.
Addiction: From Latin addictiōn-, addictiō, from addīcere, to favor, from ad- + dīcere to say.

Related Terms

Epigenome: The complete description of all the chemical modifications to the DNA and histone proteins of an organism.
Histone Modification: A covalent post-translational modification to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation.
DNA Methylation: A biochemical process by which methyl groups are added to the DNA molecule.
Neuroplasticity: The ability of neural networks in the brain to change through growth and reorganization.
Drug Tolerance: A pharmacological concept describing subjects' reduced reaction to a drug following its repeated use.
Withdrawal Syndrome: A group of symptoms that occur following the abrupt discontinuation or decrease in intake of medications or recreational drugs.

External links

Medical encyclopedia article on Epigenetics of cocaine addiction
Wikipedia's article - Epigenetics of cocaine addiction

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