Embryo cryopreservation
Embryo cryopreservation is a procedure that allows embryos to be preserved for future use. This is achieved by cooling the embryos to sub-zero temperatures, typically in liquid nitrogen, to halt all biological activity and preserve them in their current state. This technique is commonly used in assisted reproductive technologies (ART) such as in vitro fertilization (IVF).
Procedure
The process of embryo cryopreservation involves several steps. First, the embryos are created through IVF. Once the embryos reach a certain stage of development, they are prepared for freezing. This involves replacing the water in the cells with a cryoprotectant to prevent ice crystals from forming and damaging the cells during freezing. The embryos are then cooled to a very low temperature, typically -196 degrees Celsius, and stored in liquid nitrogen until they are needed.
Uses
Embryo cryopreservation is used in several situations. It allows couples undergoing IVF to have multiple attempts at pregnancy from a single cycle of egg retrieval. It also allows for the preservation of fertility for individuals or couples who are facing treatments or conditions that may affect their fertility, such as chemotherapy or radiation therapy. Additionally, it provides an option for couples who have ethical or religious objections to discarding unused embryos after IVF.
Risks and Considerations
While embryo cryopreservation is generally considered safe, there are some risks and considerations. There is a small risk of damage to the embryos during the freezing and thawing process. Additionally, not all embryos will survive the process, and those that do may not result in a successful pregnancy. There are also ethical and legal considerations related to the storage and disposition of frozen embryos.
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Contributors: Prab R. Tumpati, MD