Elbasvir/grazoprevir
Elbasvir/Grazoprevir
Elbasvir/Grazoprevir (pronunciation: el-BAS-vir/GRAS-oh-PRE-vir) is a fixed-dose combination medication used in the treatment of hepatitis C. It contains two antiviral drugs: Elbasvir and Grazoprevir.
Etymology
The names "Elbasvir" and "Grazoprevir" are derived from the names of the two active ingredients in the medication. The origins of these names are not well-documented, but they are likely derived from scientific nomenclature related to the chemical structures or mechanisms of action of the drugs.
Usage
Elbasvir/Grazoprevir is used to treat chronic hepatitis C infection, specifically genotypes 1 and 4. It is often used in patients who have not responded to other treatments or who have certain pre-existing medical conditions.
Mechanism of Action
Elbasvir is a NS5A inhibitor, which means it blocks a protein that the hepatitis C virus needs to replicate. Grazoprevir is a protease inhibitor, which means it blocks a different protein that the virus needs to reproduce. Together, these two drugs can stop the virus from multiplying and can help the body's immune system clear the infection.
Side Effects
Common side effects of Elbasvir/Grazoprevir include fatigue, headache, and nausea. More serious side effects can include liver problems and reactivation of hepatitis B in people who have previously been infected with that virus.
Related Terms
External links
- Medical encyclopedia article on Elbasvir/grazoprevir
- Wikipedia's article - Elbasvir/grazoprevir
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