Ehrlichia chaffeensis
Ehrlichia chaffeensis
Ehrlichia chaffeensis (pronounced: er-lik-ee-a shaf-ee-en-sis) is a Rickettsiales order bacteria that is responsible for causing the disease Ehrlichiosis, specifically human monocytic ehrlichiosis (HME).
Etymology
The name Ehrlichia chaffeensis is derived from the German microbiologist Paul Ehrlich, who made significant contributions to the field of hematology, immunology, and chemotherapy. The species name chaffeensis is derived from Fort Chaffee, Arkansas, where the first case of HME was identified.
Description
Ehrlichia chaffeensis is an obligate intracellular parasite that infects monocytes and macrophages. It is transmitted to humans through the bite of an infected lone star tick (Amblyomma americanum). The bacteria enter the host cells and replicate within a membrane-bound vacuole, forming clusters known as morulae.
Symptoms
Infection with Ehrlichia chaffeensis can cause a range of symptoms, including fever, headache, muscle aches, and fatigue. More severe symptoms can include leukopenia, thrombocytopenia, and elevated liver enzymes.
Diagnosis and Treatment
Diagnosis of Ehrlichia chaffeensis infection is typically made through serology or PCR testing. Treatment usually involves the use of the antibiotic doxycycline.
Related Terms
- Ehrlichiosis
- Rickettsiales
- Monocytes
- Macrophages
- Morulae
- Leukopenia
- Thrombocytopenia
- Serology
- PCR
- Doxycycline
External links
- Medical encyclopedia article on Ehrlichia chaffeensis
- Wikipedia's article - Ehrlichia chaffeensis
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