Duke

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Duke (medical term)

Duke (/djuːk/), in the field of medicine, refers to a classification system used to stage colorectal cancer. The Duke staging system was developed by Dr. Cuthbert Esquire Dukes in the 1930s.

Etymology

The term "Duke" is derived from the surname of Dr. Cuthbert Esquire Dukes, a pathologist at St Mark's Hospital in London, who first proposed the system in 1932.

Pronunciation

The term is pronounced as /djuːk/.

Duke Staging System

The Duke staging system is a method used to classify the extent of colorectal cancer. It is based on the depth of tumor invasion, the involvement of lymph nodes, and the presence of distant metastases.

  • Duke A: The cancer is confined to the inner lining of the colon.
  • Duke B: The cancer has spread to the muscle layer of the colon wall.
  • Duke C: The cancer has spread to at least one lymph node.
  • Duke D: The cancer has spread to other parts of the body (metastasized).

Related Terms

  • Colorectal cancer: A cancer that starts in the colon or the rectum.
  • Lymph node: Small, bean-shaped organs that produce and store cells that fight infection and disease.
  • Metastasis: The spread of cancer cells from the place where they first formed to another part of the body.
  • Pathologist: A doctor who specializes in interpreting laboratory tests and evaluating cells, tissues, and organs to diagnose disease.

See Also

External links

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