Drug-induced angioedema

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Drug-induced angioedema is a medical condition characterized by swelling in the deep layers of the skin, often as a result of an adverse reaction to certain medications.

Pronunciation

The term is pronounced as drug-in-duced an-gee-o-eh-dee-ma.

Etymology

The term angioedema is derived from the Greek words angeion (meaning vessel) and oedema (meaning swelling). The prefix drug-induced is used to specify that the condition is caused by the intake of certain drugs.

Definition

Drug-induced angioedema is a type of angioedema that is caused by the intake of certain medications. It is characterized by the rapid swelling of the skin, mucosa, and submucosal tissues. This condition can occur on any part of the body but is most commonly seen on the face, lips, tongue, throat, and genitals.

Causes

The most common cause of drug-induced angioedema is the use of angiotensin-converting enzyme inhibitors (ACE inhibitors), a type of medication commonly used to treat high blood pressure and heart failure. Other medications that can cause this condition include nonsteroidal anti-inflammatory drugs (NSAIDs), angiotensin II receptor blockers (ARBs), and certain antibiotics and chemotherapy drugs.

Symptoms

The symptoms of drug-induced angioedema can vary depending on the severity of the condition. They typically include swelling of the skin, mucosa, and submucosal tissues, which can cause discomfort and difficulty breathing or swallowing. Other symptoms may include redness, warmth, and pain in the affected area.

Treatment

The treatment for drug-induced angioedema typically involves discontinuing the medication that caused the condition and treating the symptoms. This may include the use of antihistamines, corticosteroids, and epinephrine to reduce swelling and inflammation.

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