Diloxanide

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Diloxanide

Diloxanide (pronunciation: dih-LOX-uh-nide) is a medication primarily used to treat amoebic infections. It is often used in combination with other antiprotozoal drugs to treat mixed infections.

Etymology

The term "Diloxanide" is derived from its chemical structure, which includes two oxanide groups and a di-substitution pattern.

Usage

Diloxanide is used in the treatment of amoebiasis, a parasitic infection caused by Entamoeba histolytica. It is effective against both the intestinal and extraintestinal forms of the disease. Diloxanide is also used in the treatment of giardiasis, another parasitic infection.

Mechanism of Action

Diloxanide works by inhibiting the growth of the amoeba, thereby preventing it from multiplying and causing further harm. It is believed to act on the cytoplasm of the amoeba, disrupting its metabolic processes.

Side Effects

Common side effects of Diloxanide include nausea, vomiting, abdominal pain, and diarrhea. In rare cases, it can cause urticaria (hives) and angioedema (swelling).

Related Terms

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