Dihydropyridine
Dihydropyridine
Dihydropyridine (pronounced: dye-hydro-pyridine) is a class of calcium channel blockers used primarily in the treatment of hypertension.
Etymology
The term "Dihydropyridine" is derived from the chemical structure of these compounds, which contain a pyridine ring that has been reduced (i.e., added hydrogen, hence "dihydro") at two positions.
Usage
Dihydropyridines are primarily used to treat hypertension, angina pectoris, and certain arrhythmias. They work by blocking the influx of calcium ions into cardiac and smooth muscle cells, thereby relaxing these cells and reducing blood pressure.
Examples
Examples of dihydropyridines include amlodipine, nifedipine, and felodipine. These drugs are often used in combination with other medications to achieve optimal blood pressure control.
Side Effects
Common side effects of dihydropyridines include edema, flushing, and headache. Less common but more serious side effects can include heart failure and hypotension.
Related Terms
- Calcium channel blockers: A class of drugs that dihydropyridines belong to.
- Hypertension: A condition that dihydropyridines are often used to treat.
- Angina pectoris: A type of chest pain that dihydropyridines can help alleviate.
- Arrhythmia: An irregular heartbeat that can sometimes be treated with dihydropyridines.
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