Detection limit

Detection limit

The detection limit, also known as the limit of detection (LOD), is the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) within a stated confidence limit (generally 1%). The detection limit is a parameter of limit tests and quantitative tests in areas such as analytical chemistry and medical testing.

Pronunciation

/dɪˈtɛkʃən lɪmɪt/

Etymology

The term "detection limit" is derived from the English words "detection" (from the Latin detectio, meaning "discovery") and "limit" (from the Latin limes, meaning "boundary").

Related Terms

• Analytical chemistry
• Limit of quantitation
• Limit of blank
• Signal-to-noise ratio
• Confidence limit

See Also

• Sensitivity (tests)
• Specificity (tests)

References

• International Union of Pure and Applied Chemistry. "Detection limit." Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).

External links

• Medical encyclopedia article on Detection limit
• Wikipedia's article - Detection limit

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