Deoxypyridinoline

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Deoxypyridinoline

Deoxypyridinoline (pronounced dee-ox-ee-pie-rid-in-o-line) is a biochemical marker used in the medical field to measure the rate of bone resorption. It is often used in the diagnosis and monitoring of osteoporosis and other bone diseases.

Etymology

The term "Deoxypyridinoline" is derived from its chemical structure. It is a pyridinium cross-link found in the collagen of bone and dentin. The prefix "deoxy-" is derived from the Greek word "de-" meaning "without" and "oxy" meaning "oxygen", indicating the absence of an oxygen atom in the molecule.

Usage

Deoxypyridinoline is excreted in the urine and can be measured using a urine test. High levels of deoxypyridinoline in the urine can indicate increased bone resorption, which may be a sign of osteoporosis or other bone diseases.

Related Terms

  • Biochemical marker: A substance that can be measured in the body and provide information about a disease or condition.
  • Bone resorption: The process by which osteoclasts break down bone and release the minerals, resulting in a transfer of calcium from bone fluid to the blood.
  • Osteoporosis: A condition in which bones become weak and brittle.
  • Bone disease: A broad term for conditions that affect the structure or function of the bone.
  • Collagen: The main structural protein in the extracellular space in the various connective tissues in the body.
  • Urine test: A type of test that may be used to detect disease, such as a urinary tract infections, kidney disease, and diabetes.

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