Defactinib

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Defactinib

Defactinib (pronounced as de-fak-ti-nib) is a type of medication used in the treatment of various types of cancer. It is a small molecule inhibitor of the FAK (Focal Adhesion Kinase) and Pyk2 (Proline-rich tyrosine kinase 2) enzymes, which are involved in the growth and spread of cancer cells.

Etymology

The name "Defactinib" is derived from the term "FAK inhibitor", indicating its function as an inhibitor of the Focal Adhesion Kinase enzyme. The prefix "de-" is a common prefix in the naming of drugs, often indicating a removal or reduction in function.

Usage

Defactinib is used in the treatment of various types of cancer, including mesothelioma, ovarian cancer, and non-small cell lung cancer. It works by inhibiting the activity of the FAK and Pyk2 enzymes, thereby preventing the growth and spread of cancer cells.

Related Terms

  • FAK (Focal Adhesion Kinase): An enzyme involved in the growth and spread of cancer cells.
  • Pyk2 (Proline-rich tyrosine kinase 2): Another enzyme involved in the growth and spread of cancer cells.
  • Mesothelioma: A type of cancer that affects the mesothelium, the thin layer of tissue that covers most of your internal organs.
  • Ovarian cancer: A type of cancer that begins in the ovaries.
  • Non-small cell lung cancer: The most common type of lung cancer.

External links

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