Dcx
Dcx (pronounced: /dɪks/), also known as Doublecortin, is a protein that in humans is encoded by the DCX gene. It is primarily associated with the development of the brain and the nervous system.
Etymology
The term "Dcx" is an abbreviation of "Doublecortin". The name "Doublecortin" is derived from the protein's role in cortical development, where it is involved in the migration of neurons. The term "cortin" is derived from the Latin "cortex", meaning "bark" or "shell", which is used to describe the outer layer of the brain.
Function
Dcx is a microtubule-associated protein and is expressed almost exclusively in immature neurons. Its function is crucial for neuronal migration, a process that allows neurons to reach their correct destination within the brain. Mutations in this gene are associated with X-linked lissencephaly and subcortical band heterotopia, two neuronal migration disorders.
Related Terms
See Also
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