Dandy

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Dandy-Walker Syndrome

Dandy-Walker Syndrome (pronounced: dan-dee-wok-er sin-drome) is a congenital brain malformation involving the cerebellum and the fluid filled spaces around it. The term is named after American neurosurgeons Walter Dandy and Arthur Earl Walker.

Etymology

The term "Dandy-Walker" is derived from the names of Walter Dandy and Arthur Earl Walker, who first described the condition in the early 20th century.

Definition

Dandy-Walker Syndrome is a congenital (present from birth) brain malformation where the cerebellum and the fluid filled spaces around it do not develop properly. The key features of this syndrome are an enlargement of the fourth ventricle (a small channel that allows fluid to flow freely between the upper and lower areas of the brain and spinal cord), a partial or complete absence of the cerebellar vermis (the area between the two cerebellar hemispheres), and cyst formation near the internal base of the skull.

Symptoms

Symptoms of Dandy-Walker Syndrome can include slow motor development, progressive enlargement of the skull, irritability, vomiting, unsteadiness, lack of muscle coordination, or other neurological signs.

Related Terms

  • Cerebellum: The part of the brain at the back of the skull in vertebrates, which coordinates and regulates muscular activity.
  • Ventricles of the brain: The ventricles of the brain are a communicating network of cavities filled with cerebrospinal fluid (CSF) and located within the brain parenchyma.
  • Cerebellar vermis: The unpaired area of the cerebellum lying between the two hemispheres.
  • Congenital disorder: A congenital disorder, also known as a congenital disease, birth defect, or anomaly, is a condition existing at or before birth regardless of cause.

See Also

External links

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