DIRC2
DIRC2 (Disrupted in Renal Carcinoma 2) is a protein that in humans is encoded by the DIRC2 gene. This gene is located on the chromosome 2 and is known to be involved in the development of renal carcinoma, a type of kidney cancer.
Function
The DIRC2 protein is a transmembrane protein that is primarily located in the endoplasmic reticulum. It is involved in the regulation of cell growth and cell division. Mutations in the DIRC2 gene can lead to the development of renal carcinoma.
Clinical significance
DIRC2 has been identified as a potential biomarker for renal carcinoma. Studies have shown that the expression of DIRC2 is significantly increased in renal carcinoma tissues compared to normal kidney tissues. This suggests that DIRC2 could be used as a diagnostic marker for renal carcinoma.
Research
Research into the DIRC2 gene and its associated protein is ongoing. Current research is focused on understanding the exact role of DIRC2 in the development of renal carcinoma and exploring its potential as a therapeutic target.
See also
References
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Contributors: Prab R. Tumpati, MD
