Cyclopentadecanolide
Cyclopentadecanolide is a macrocyclic musk compound that is commonly used in the perfume industry due to its strong musk odor. It is a synthetic compound, meaning it is not naturally occurring but is instead created in a laboratory setting.
Chemical Structure
Cyclopentadecanolide, also known as Exaltolide, has the chemical formula C_15H_28O_2. It is a 15-membered lactone and is one of the simplest macrocyclic musk compounds. The structure of cyclopentadecanolide consists of a 15-membered ring with an ester functional group (lactone) and a single hydroxyl group.
Uses
Cyclopentadecanolide is primarily used in the perfume industry due to its strong musk odor. It is often used in combination with other musk compounds to create a variety of different scents. In addition to its use in perfumes, cyclopentadecanolide is also used in soaps, detergents, and other personal care products.
Synthesis
The synthesis of cyclopentadecanolide involves the reaction of pentadecanolide with a strong base such as sodium hydroxide (NaOH) or potassium hydroxide (KOH). This reaction results in the formation of a cyclic ester, or lactone, which is then reduced to form cyclopentadecanolide.
Safety
As with all chemicals, proper safety precautions should be taken when handling cyclopentadecanolide. It is recommended to wear protective clothing, gloves, and eye protection when handling this compound. In case of skin contact, wash with plenty of soap and water. In case of eye contact, rinse immediately with plenty of water and seek medical advice.
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Contributors: Prab R. Tumpati, MD