Councilman body
Councilman body (pronunciation: /ˈkaʊnsəlmən ˈbɒdi/) is a term used in the field of Pathology to describe a type of cell death, specifically referring to the necrotic hepatocytes often seen in viral Hepatitis. The term is named after American pathologist Frank Burr Mallory, who first described these bodies, but it is often attributed to his mentor, William Councilman, hence the name.
Etymology
The term "Councilman body" is derived from the name of William Councilman, a prominent American pathologist in the late 19th and early 20th centuries. Councilman was a pioneer in the study of liver diseases, and his work laid the foundation for much of our current understanding of the pathology of the liver.
Description
Councilman bodies are eosinophilic (acidophilic), round or oval inclusions found in the cytoplasm of hepatocytes. They are a result of hydropic degeneration, a form of cellular degeneration, and are often associated with viral hepatitis, particularly Hepatitis B and Hepatitis C.
Related Terms
- Hepatocyte: The main cell type in the liver, which makes up 70-85% of the liver's mass.
- Necrosis: The death of cells or tissues from severe injury or disease, especially in a localized area of the body.
- Eosinophilic: Referring to cells or material that stain readily with eosin, a red acidic dye.
- Hydropic degeneration: A form of cellular degeneration characterized by the swelling of cells due to injury to the cell membrane.
See Also
External links
- Medical encyclopedia article on Councilman body
- Wikipedia's article - Councilman body
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