Compensatory growth (organ)
Compensatory Growth (Organ)
Compensatory growth is a biological process that allows an organ to regenerate and grow after damage or removal. This phenomenon is observed in various organisms, including humans, and is particularly prominent in the liver.
Pronunciation
/kəmˈpensəˌtôrē grōTH/
Etymology
The term "compensatory growth" is derived from the Latin word "compensare" which means "to weigh one thing against another", and the Old English word "groeiþ" which means "increase, growth".
Definition
Compensatory growth refers to the ability of an organ to increase its cell proliferation rate in response to damage or partial removal. This process allows the organ to restore its original size and function. The most well-known example of this phenomenon is the liver, which can regenerate to its original size even after 70% of it has been removed or damaged.
Mechanism
The exact mechanism of compensatory growth is not fully understood, but it is believed to involve a complex interplay of growth factors, cytokines, and other signaling molecules. These factors stimulate the remaining cells in the organ to divide and proliferate, thereby increasing the size of the organ.
Related Terms
- Regeneration: The process by which organisms replace lost or damaged body parts.
- Cell Proliferation: The process that results in an increase in the number of cells, and is defined by the balance between cell divisions and cell loss through cell death or differentiation.
- Liver Regeneration: The process by which the liver is able to replace lost liver tissue from growth from the remaining tissue.
- Cytokines: A broad and loose category of small proteins that are important in cell signaling.
See Also
External links
- Medical encyclopedia article on Compensatory growth (organ)
- Wikipedia's article - Compensatory growth (organ)
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