Chymopapain

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Chymopapain

Chymopapain (pronounced: kai-mo-pa-pain) is a proteolytic enzyme extracted from the latex of the papaya plant (Carica papaya).

Etymology

The term "Chymopapain" is derived from the Greek word "chymos" meaning juice and "papain" from the papaya plant from which it is extracted.

Description

Chymopapain is a cysteine protease that has been used in medical applications for its ability to break down certain proteins in the body. It is most commonly used in the treatment of herniated discs, a condition where the soft center of a spinal disc pushes through a crack in the tougher exterior casing.

Medical Use

In a procedure known as Chemonucleolysis, Chymopapain is injected directly into the herniated disc. The enzyme works by breaking down the proteins in the disc, reducing its size and relieving pressure on the nerves. This can help to alleviate pain and other symptoms associated with a herniated disc.

Related Terms

  • Proteolytic enzyme: An enzyme that performs proteolysis, protein catabolism by hydrolysis of peptide bonds.
  • Cysteine protease: A type of protease enzyme that uses a cysteine residue in its active site.
  • Herniated disc: A condition which can occur in any part of the spine and can cause pain, numbness or weakness in an arm or leg.
  • Chemonucleolysis: A type of surgery to reduce the size of a herniated disc.

See Also

External links

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