Chemosensitivity assay

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Chemosensitivity Assay

A Chemosensitivity assay (pronounced: kee-mo-sen-si-tiv-i-tee as-say) is a laboratory test that measures the sensitivity and resistance of tumor cells to chemotherapy drugs. The term originates from the Greek words "chemia" meaning chemistry and "sensitivity" from the Latin "sensitivus", meaning easily affected.

Definition

A Chemosensitivity assay is a type of in vitro test that is used to determine the effectiveness of different chemotherapy drugs on a patient's cancer cells. This test is often used to help guide treatment decisions in oncology.

Procedure

In a Chemosensitivity assay, a sample of the patient's tumor is collected during biopsy or surgery. The tumor cells are then exposed to different chemotherapy drugs in the laboratory. The response of the tumor cells to these drugs is measured to determine which drugs are most effective at killing the tumor cells.

Importance

Chemosensitivity assays can help to personalize cancer treatment by identifying the most effective chemotherapy drugs for a particular patient's tumor. This can help to avoid the use of ineffective drugs and reduce the risk of unnecessary side effects.

Related Terms

  • Chemoresistance: The resistance of cancer cells to chemotherapy drugs.
  • In vitro: A process performed or taking place in a test tube, culture dish, or elsewhere outside a living organism.
  • Biopsy: The removal of cells or tissues for examination by a pathologist.
  • Oncology: The study of cancer and treatment of cancer.

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