CT Value

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CT Value

CT Value (pronounced as C-T Value), also known as Cycle Threshold Value, is a term used in Real-Time Polymerase Chain Reaction (RT-PCR) testing, particularly in the context of COVID-19 testing.

Pronunciation

C-T Value

Etymology

The term 'CT Value' is derived from the words 'Cycle Threshold'. 'Cycle' refers to the number of cycles in a PCR test, and 'Threshold' refers to the point at which a positive result can be determined.

Definition

The CT Value is the number of cycles needed in a RT-PCR test to amplify the viral RNA to reach a detectable level. The lower the CT Value, the higher the amount of viral RNA in the sample. Conversely, a higher CT Value indicates a lower amount of viral RNA in the sample.

Related Terms

  • Real-Time Polymerase Chain Reaction (RT-PCR): A laboratory technique used in molecular biology to amplify and simultaneously monitor the amplification of targeted DNA molecules.
  • Viral Load: The amount of virus in a person's blood.
  • RNA: Ribonucleic acid, a nucleic acid present in all living cells. Its principal role is to act as a messenger carrying instructions from DNA for controlling the synthesis of proteins.
  • COVID-19: An infectious disease caused by a newly discovered coronavirus.
  • Coronavirus: A type of virus. There are many different kinds, and some of them can cause disease.

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