CTLA-4
| CTLA-4 | |
|---|---|
| Term | CTLA-4 |
| Short definition | CTLA-4 - A protein found on T cells (a type of immune cell) that helps keep the body's immune responses in check. When CTLA-4 is attached to another protein called B7, it helps keep T cells from killing other cells, including cancer cells. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
CTLA-4 - A protein found on T cells (a type of immune cell) that helps keep the body's immune responses in check. When CTLA-4 is attached to another protein called B7, it helps keep T cells from killing other cells, including cancer cells. Some cancer drugs called immune checkpoint inhibitors are used to block CTLA-4. When this protein is blocked, the immune system's "brakes" are released and the ability of T cells to kill cancer cells is increased
External links
- Medical encyclopedia article on CTLA-4
- Wikipedia's article - CTLA-4
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