CCR2

CCR2

CCR2 (pronounced "C-C-R-two"), also known as CC chemokine receptor type 2, is a protein that in humans is encoded by the CCR2 gene.

Pronunciation

• IPA: /ˌsiːˌsiːˈɑːrˈtuː/

Etymology

The term CCR2 is an abbreviation of CC Chemokine Receptor type 2. The "CC" refers to the two adjacent cysteines (amino acids), while "chemokine receptor" refers to the type of protein it is. The "2" indicates that it is the second of its kind to be discovered.

Function

CCR2 is a receptor for several monocyte chemoattractant proteins (MCPs), which are chemokines that specifically mediate monocyte chemotaxis. Monocytes and macrophages are the primary target cells of this receptor. This receptor may play a role in the accumulation and migration of monocytes into inflammatory sites and in normal cell migration processes.

Related Terms

• Chemokine
• Monocyte
• Chemotaxis
• Protein
• Gene
• Amino acid
• Cell migration

See Also

• CCR5
• CCR3
• CCR4

External links

• Medical encyclopedia article on CCR2
• Wikipedia's article - CCR2

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