Buffy coat

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Buffy Coat

The Buffy Coat (pronounced: /ˈbʌfi koʊt/) is a thin layer of leukocytes (white blood cells) and platelets that forms between the plasma and red blood cells in a sample of anticoagulated blood that has been centrifuged.

Etymology

The term "Buffy Coat" is derived from the characteristic buff-colored appearance of this layer in a centrifuged blood sample. The color is due to the high concentration of white blood cells and platelets.

Related Terms

  • Leukocytes: Also known as white blood cells, these are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
  • Platelets: Small, colorless cell fragments in our blood that form clots and stop or prevent bleeding.
  • Plasma: The liquid component of blood, in which the blood cells are suspended.
  • Red Blood Cells: Also known as erythrocytes, these are the most common type of blood cell and the principal means of delivering oxygen to body tissues.
  • Anticoagulated Blood: Blood that has been treated with an anticoagulant to prevent clotting.
  • Centrifugation: A process that involves the use of the centrifugal force for the sedimentation of heterogeneous mixtures with a centrifuge.

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