Bronchial leiomyoma
A rare benign tumor of the bronchial tubes
Bronchial leiomyoma is a rare type of benign tumor that arises from the smooth muscle tissue of the bronchial tubes. These tumors are part of a broader category of leiomyomas, which are smooth muscle tumors that can occur in various parts of the body.
Pathophysiology
Bronchial leiomyomas originate from the smooth muscle cells that are part of the bronchial wall. These tumors are non-cancerous and typically grow slowly. They can cause symptoms by obstructing the airways, leading to respiratory issues. The exact cause of bronchial leiomyomas is not well understood, but they are thought to arise from genetic mutations that lead to the proliferation of smooth muscle cells.
Clinical Presentation
Patients with bronchial leiomyoma may present with symptoms such as cough, dyspnea (shortness of breath), wheezing, and hemoptysis (coughing up blood). The symptoms are often due to the obstruction of the bronchial tubes by the tumor. In some cases, the tumor may be asymptomatic and discovered incidentally during imaging studies for other conditions.
Diagnosis
The diagnosis of bronchial leiomyoma typically involves imaging studies such as chest X-ray and computed tomography (CT) scan, which can reveal the presence of a mass in the bronchial tubes. Bronchoscopy may be performed to visualize the tumor directly and obtain a biopsy for histological examination. The biopsy will show the characteristic features of a leiomyoma, including spindle-shaped smooth muscle cells.
Treatment
The primary treatment for bronchial leiomyoma is surgical resection. The goal of surgery is to remove the tumor and relieve any obstruction of the airways. In some cases, less invasive procedures such as bronchoscopic resection may be possible. Since bronchial leiomyomas are benign, complete surgical removal usually results in a cure, and recurrence is rare.
Prognosis
The prognosis for patients with bronchial leiomyoma is generally excellent following surgical resection. These tumors do not metastasize, and once removed, they typically do not recur. Patients can expect a full recovery and return to normal respiratory function after treatment.
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Contributors: Prab R. Tumpati, MD