Brequinar
Brequinar (pronounced breh-KWIN-ar) is a type of antineoplastic agent that is used in the treatment of various types of cancer. It is a dihydroorotate dehydrogenase inhibitor, which means it works by blocking the action of an enzyme that is necessary for the growth of cancer cells.
Etymology
The term "Brequinar" is derived from the chemical name of the drug, which is 6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid. The "-quin-" in the name refers to the quinoline part of the molecule, while the "-ar" at the end is a common suffix used in the names of drugs.
Usage
Brequinar is used in the treatment of a variety of cancers, including leukemia, lymphoma, and solid tumors. It is usually administered intravenously, and the dosage and frequency of administration depend on the type and stage of the cancer being treated.
Related Terms
- Antineoplastic agent: A type of drug that inhibits the growth and spread of cancer cells.
- Dihydroorotate dehydrogenase: An enzyme that is involved in the synthesis of pyrimidines, which are essential components of DNA and RNA.
- Leukemia: A type of cancer that affects the blood and bone marrow.
- Lymphoma: A type of cancer that begins in the cells of the immune system.
- Solid tumor: A type of cancer that begins in the cells of a specific organ or tissue.
See Also
External links
- Medical encyclopedia article on Brequinar
- Wikipedia's article - Brequinar
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