B type inclusion
B Type Inclusion is a term used in the field of Pathology to describe a specific type of cellular inclusion. These inclusions are typically found in cells infected with certain types of viruses, such as the Herpes simplex virus and Cytomegalovirus.
Overview
B Type Inclusions are intranuclear or intracytoplasmic aggregates of viral or cellular components that are often visible under a light microscope. They are typically associated with viral infections, and their presence can be a useful diagnostic indicator of certain diseases.
Characteristics
B Type Inclusions are characterized by their distinct morphology. They are typically large, round, and have a glassy appearance. They may be single or multiple within a cell, and are often surrounded by a clear halo. The inclusions are usually eosinophilic, meaning they stain red or pink with Eosin stain.
Associated Viruses
B Type Inclusions are most commonly associated with the Herpes simplex virus and Cytomegalovirus. In cells infected with these viruses, the inclusions are typically found within the nucleus. However, they can also be found in the cytoplasm in some cases.
Clinical Significance
The presence of B Type Inclusions in a cell can be a useful diagnostic indicator of a viral infection. They are often found in cells from patients with Herpes simplex encephalitis or Cytomegalovirus infection. In addition, they can also be found in cells from patients with other diseases, such as Pneumonia and Mononucleosis.
See Also
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Contributors: Prab R. Tumpati, MD