BCAR1
BCAR1 BCAR1 is a gene that encodes a protein known as breast cancer anti-estrogen resistance 1. This protein plays a crucial role in cell adhesion and migration processes. Mutations in the BCAR1 gene have been associated with various cancers, including breast cancer.
Function
The BCAR1 protein is involved in signaling pathways that regulate cell adhesion and migration. It interacts with other proteins to modulate cellular processes such as cell growth and survival. Dysregulation of BCAR1 expression can lead to abnormal cell behavior and contribute to cancer development.
Clinical Significance
Mutations in the BCAR1 gene have been linked to anti-estrogen resistance in breast cancer patients. Understanding the role of BCAR1 in cancer progression may help in developing targeted therapies for patients with BCAR1 mutations.
Research
Research on BCAR1 is ongoing to elucidate its precise role in cancer development and progression. Studies are focused on identifying potential therapeutic targets associated with BCAR1 mutations.
See also
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Contributors: Prab R. Tumpati, MD
