Autoschizis
Autoschizis (pronounced: auto-ski-zis) is a form of programmed cell death or apoptosis that is characterized by the self-excising of the cell's own cytoplasmic content.
Etymology
The term "Autoschizis" is derived from the Greek words "auto" meaning self, and "schizein" meaning to split. Thus, it literally translates to "self-splitting".
Overview
Autoschizis is a unique form of cell death that is distinct from other forms of apoptosis such as necrosis and autophagy. It is characterized by a sequence of morphological changes that lead to the self-excising of the cell's own cytoplasmic content. This process is often associated with oxidative stress and is thought to be a protective mechanism against cancer.
Process
The process of autoschizis begins with the cell shrinking and the nucleus condensing. This is followed by the formation of blebs on the cell surface, which eventually rupture and release the cell's cytoplasmic content. The remaining cell then undergoes a process of self-digestion, leading to its eventual death.
Related Terms
- Apoptosis: A form of programmed cell death that occurs in multicellular organisms.
- Necrosis: A form of cell injury which results in the premature death of cells in living tissue.
- Autophagy: A cellular process that involves the degradation of a cell's own components through the lysosomal machinery.
See Also
External links
- Medical encyclopedia article on Autoschizis
- Wikipedia's article - Autoschizis
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