Atabrine
Atabrine (pronounced: a-ta-brine) is a synthetic compound with antimalarial properties. It is also known as quinacrine or mepacrine.
Etymology
The term "Atabrine" is derived from the chemical structure of the compound, which is an acridine derivative. The name "quinacrine" comes from the combination of quinine and acridine, two substances that were used in the early treatment of malaria.
Usage
Atabrine was widely used during World War II as an antimalarial drug. It was particularly effective against Plasmodium vivax, one of the parasites that cause malaria. Today, it is less commonly used due to the development of other antimalarial drugs, but it is still used in some cases, particularly for the treatment of giardiasis, a parasitic infection of the small intestine.
Side Effects
Some of the common side effects of Atabrine include nausea, vomiting, diarrhea, and stomach cramps. In rare cases, it can cause yellowing of the skin or eyes (jaundice), which is usually reversible once the medication is stopped.
Related Terms
External links
- Medical encyclopedia article on Atabrine
- Wikipedia's article - Atabrine
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