Armillifer armillatus
A parasitic pentastomid infecting reptiles and occasionally humans
Armillifer armillatus is a species of parasitic pentastomid belonging to the family Porocephalidae. It primarily infects reptiles, particularly snakes, but can also infect humans, causing a condition known as pentastomiasis.
Morphology
Armillifer armillatus exhibits a segmented, worm-like body typical of pentastomids. The adult form is characterized by its elongated body, which can reach up to 13 cm in length. The body is divided into numerous segments, each bearing a pair of hooks used for attachment to the host's tissues.
Life Cycle
The life cycle of Armillifer armillatus involves multiple hosts. The adult parasites reside in the respiratory tract of reptiles, where they reproduce. Eggs are expelled from the host through respiratory secretions and are ingested by an intermediate host, often a small mammal or human. Inside the intermediate host, the larvae hatch and migrate to various tissues, forming cysts. When a reptile consumes the infected intermediate host, the larvae develop into adults, completing the cycle.
Pathogenesis
In reptiles, Armillifer armillatus typically causes mild respiratory symptoms. However, in humans, the larvae can cause more severe symptoms depending on the location and number of cysts formed. Common symptoms include abdominal pain, fever, and respiratory distress. Severe cases can lead to organ damage and require medical intervention.
Diagnosis
Diagnosis of Armillifer armillatus infection in humans is often challenging due to the non-specific nature of symptoms. Imaging techniques such as X-ray and CT scan can reveal the presence of calcified cysts in tissues. Serological tests may also aid in diagnosis.
Treatment
Treatment of human pentastomiasis caused by Armillifer armillatus is primarily supportive. Surgical removal of cysts may be necessary in severe cases. Antiparasitic medications have limited efficacy, and prevention through avoiding consumption of undercooked or raw reptile meat is recommended.
Prevention
Preventive measures include proper cooking of reptile meat and avoiding contact with infected reptiles. Public health education is crucial in endemic areas to reduce the risk of transmission to humans.
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Contributors: Prab R. Tumpati, MD