Anne O'Garra

Anne O'Garra (cropped)

British immunologist

Anne O'Garra

Nationality	British
Known for	Research on cytokines and immune regulation

Anne O'Garra is a British immunologist known for her pioneering research in the field of cytokines and immune regulation. She is currently a group leader at the Francis Crick Institute in London.

Education and Early Career

Anne O'Garra received her undergraduate degree in Biochemistry from the University of London. She went on to complete her PhD in Immunology at the same institution. Her early research focused on the role of cytokines in the immune response.

Research and Contributions

O'Garra's research has significantly advanced the understanding of cytokine networks and their role in immune regulation. She has made notable contributions to the understanding of how interleukin-10 (IL-10) functions as an anti-inflammatory cytokine. Her work has implications for the treatment of various autoimmune diseases and infectious diseases.

Cytokines and Immune Regulation

One of O'Garra's major research areas is the study of cytokines, which are small proteins important in cell signaling. Her work has elucidated the mechanisms by which cytokines regulate the immune response, particularly in the context of inflammation and autoimmunity.

Interleukin-10 (IL-10)

O'Garra has extensively studied interleukin-10 (IL-10), a cytokine with potent anti-inflammatory properties. Her research has shown how IL-10 can inhibit the function of macrophages and dendritic cells, thereby reducing inflammation and preventing tissue damage during immune responses.

Awards and Honors

Anne O'Garra has received numerous awards for her contributions to immunology, including recognition from various scientific societies and institutions. She is a fellow of the Royal Society and has been awarded honorary degrees from several universities.

Current Work

O'Garra continues to lead a research group at the Francis Crick Institute, where she investigates the complex interactions between cytokines and the immune system. Her current projects include studying the role of cytokines in tuberculosis and other chronic infections.

See Also

• Immunology
• Cytokine
• Interleukin-10
• Francis Crick Institute
• Autoimmune disease

References

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