Ann Arbor staging

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Ann Arbor staging is a classification system used primarily in the field of Oncology to stage Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma. It was first introduced in 1971 at a meeting of Cancer specialists in Ann Arbor, Michigan, hence the name.


The term is pronounced as "an ar-bor stay-jing".


The term derives its name from the city of Ann Arbor in Michigan, USA, where the staging system was first proposed in 1971 during a meeting of the Cotswolds conference.


The Ann Arbor staging system is a method used to classify the extent of disease in patients with Hodgkin's and Non-Hodgkin's Lymphoma. It is based on the number of lymph node regions involved and whether the disease has spread beyond the lymph nodes.


The Ann Arbor staging system includes four stages:

  • Stage I: Involvement of a single lymph node region or a single extralymphatic organ or site.
  • Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm.
  • Stage III: Involvement of lymph node regions on both sides of the diaphragm.
  • Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs.

Each stage can further be classified as A or B depending on the presence (B) or absence (A) of systemic symptoms such as fever, night sweats, and weight loss.

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