Angiotensin-Converting Enzyme

Angiotensin-Converting Enzyme (pronunciation: an·​gio·​ten·​sin-con·​vert·​ing en·​zyme) is a protein that plays a crucial role in the RAS. It is often abbreviated as ACE.

Etymology

The term "Angiotensin-Converting Enzyme" is derived from its function. It converts Angiotensin I into Angiotensin II, a potent vasoconstrictor, in the body's blood pressure regulation system.

Function

The primary function of the Angiotensin-Converting Enzyme is to convert Angiotensin I, a relatively inactive molecule, into Angiotensin II. Angiotensin II is a potent vasoconstrictor, which means it narrows the blood vessels. This narrowing can increase blood pressure. Angiotensin II also stimulates the release of Aldosterone, a hormone that promotes the absorption of sodium and water in the kidneys, which can further increase blood pressure.

Related Terms

• Angiotensin I
• Angiotensin II
• Renin-Angiotensin System
• Aldosterone
• Vasoconstriction
• Blood Pressure

See Also

• ACE Inhibitors
• Hypertension

External links

• Medical encyclopedia article on Angiotensin-Converting Enzyme
• Wikipedia's article - Angiotensin-Converting Enzyme

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