Angiokeratoma

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Angiokeratoma
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Small, dark red to purple papules on the skin
Complications	Bleeding, ulceration
Onset	Varies, often in adulthood
Duration	Chronic
Types	N/A
Causes	Vascular malformations
Risks	Fabry disease, Klippel–Trénaunay syndrome
Diagnosis	Clinical diagnosis, biopsy
Differential diagnosis	Melanoma, hemangioma, verruca
Prevention	N/A
Treatment	Laser therapy, cryotherapy, surgical excision
Medication	N/A
Prognosis	N/A
Frequency	Common
Deaths	N/A

Introduction

Angiokeratoma (pronounced an-je-o-ker-at-o'-mah) is a rare skin condition characterized by small, dark vascular lesions that resemble warts. These lesions typically develop on dilated blood vessels in individuals with certain predisposing conditions, such as chilblains.

Definition and Characteristics

Angiokeratoma is a medical term combining "angio-" (referring to blood vessels), "kerat-" (from Greek 'Kerat,' meaning horn, indicating a hard texture), and "-oma" (denoting a tumor or growth). The condition is marked by:

• Warty-looking growths on dilated vessels.
• Dark vascular spots ranging in size from pin-points to pin-heads.
• A predilection for occurring in childhood.

Microscopic view of Angiokeratoma

Pathogenesis and Etiology

• Chilblains: Angiokeratomas often develop as an attack of chilblains is subsiding. Chilblains are small, itchy, red patches that can appear after exposure to cold.
• Vascular Dilatation: The condition involves the dilatation of blood vessels near the skin's surface.

Clinical Presentation

• Angiokeratoma lesions typically appear on the extremities.
• They are often dark red to black in color and have a rough surface.
• The condition is more common in children, but can occasionally be seen in adults.

Diagnosis

Diagnosis of angiokeratoma generally involves:

• Clinical examination of the characteristic lesions.
• Dermatoscopic evaluation to observe the vascular patterns.
• Biopsy and histopathological examination in uncertain cases.

Treatment and Management

While angiokeratomas are usually benign and asymptomatic, treatment options may be considered for cosmetic reasons or discomfort, including:

• Laser therapy.
• Cryotherapy.
• Surgical excision in rare cases.

Complications

In rare instances, angiokeratomas may be associated with systemic diseases, or complications such as bleeding may occur from the lesions.

Prognosis

The prognosis for isolated angiokeratomas is generally good, especially in children where the condition may resolve spontaneously.

Epidemiology

This condition is relatively rare and has a higher incidence in individuals with a history of chilblains or other vascular conditions.

External Links

• DermNet NZ: Angiokeratoma
• National Center for Biotechnology Information: Angiokeratoma

See Also

• Chilblains
• Dermatology
• Vascular skin lesions
• Pediatric dermatology

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