Amelogenesis

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Amelogenesis

Amelogenesis (/əˌmɛloʊˈdʒɛnɪsɪs/) is the intricate process by which teeth enamel, the hardest substance in the human body, is formed. This process involves several stages, including the secretory and maturation stages, and is carried out by specialized cells known as ameloblasts.

Etymology

The term "amelogenesis" is derived from the Greek words "amelos" meaning enamel and "genesis" meaning origin or formation.

Process

Amelogenesis begins with the secretory stage, where ameloblasts secrete a protein matrix and an enamel matrix. This is followed by the maturation stage, where the enamel matrix becomes mineralized to form mature enamel.

Related Terms

  • Ameloblasts: The cells responsible for the formation of tooth enamel.
  • Enamel: The hard, outermost layer of a tooth.
  • Secretory stage: The first stage of amelogenesis, where the enamel matrix is formed.
  • Maturation stage: The final stage of amelogenesis, where the enamel matrix is mineralized to form mature enamel.

Disorders

Disorders of amelogenesis, known as amelogenesis imperfecta, can lead to a variety of dental problems, including tooth sensitivity, increased risk of cavities, and aesthetic concerns.

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