Alpha-taxilin
Alpha-taxilin is a protein that in humans is encoded by the TXLNA gene. This protein is part of the taxilin family, which includes beta-taxilin and gamma-taxilin. Alpha-taxilin is involved in various cellular processes, including intracellular trafficking and cell proliferation.
Function
Alpha-taxilin is known to interact with syntaxin family members, proteins that are involved in vesicular transport. It is thought to play a role in the regulation of vesicle fusion, a process that is essential for intracellular trafficking. Additionally, alpha-taxilin has been implicated in cell proliferation, suggesting it may have a role in cell growth and division.
Clinical significance
Alterations in the TXLNA gene, which encodes alpha-taxilin, have been associated with a variety of diseases. For example, overexpression of alpha-taxilin has been observed in certain types of cancer, suggesting it may contribute to tumor growth and progression. Further research is needed to fully understand the role of alpha-taxilin in disease.
See also
References
External links
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Contributors: Prab R. Tumpati, MD
