Adverse Drug Reaction

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Adverse Drug Reaction

An Adverse Drug Reaction (ADR) (pronounced: ad-verse drug ree-ak-shun) is an unwanted or harmful reaction experienced following the administration of a drug or combination of drugs under normal conditions of use and is suspected to be related to the drug. The term is often used interchangeably with side effects.

Etymology

The term "Adverse Drug Reaction" is derived from the English language. "Adverse" comes from the Latin word "adversus" meaning "against", "Drug" is derived from the Old French "drogue" meaning "medicine", and "Reaction" comes from the Latin "reactio" meaning "a response".

Types of Adverse Drug Reactions

There are two main types of ADRs: type A and type B.

  • Type A reactions are predictable from the known pharmacology of a drug and are usually dose-dependent. They are the most common type of ADR.
  • Type B reactions are unpredictable, not dose-dependent, and are usually due to the individual's immune system reacting to the drug.

Related Terms

  • Pharmacovigilance - The science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problems.
  • Drug Interaction - A situation in which a substance affects the activity of a drug when both are administered together.
  • Drug Allergy - An allergic reaction to a drug, which is a common cause of adverse drug reactions.

See Also

References

External links

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