ABT-888
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| ABT-888 | |
|---|---|
| Term | ABT-888 |
| Short definition | ABT-888 - A substance being studied for the treatment of breast cancer caused by mutations (changes) in the BRCA1 and BRCA2 genes. It is also being studied in the treatment of other types of cancer. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
ABT-888 - A substance being studied for the treatment of breast cancer caused by mutations (changes) in the BRCA1 and BRCA2 genes. It is also being studied in the treatment of other types of cancer. It blocks an enzyme involved in many cell functions, including repairing DNA damage. DNA damage can be caused by normal cell action, UV light, some cancer drugs, and radiation used to treat cancer. ABT-888 can kill cancer cells. It is a type of poly(ADP-ribose) polymerase inhibitor. Also called PARP-1 inhibitor ABT-888 and veliparib
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