40S ribosomal protein S10

Ideogram human chromosome 6

40S ribosomal protein S10 is a vital component of the small ribosomal subunit in cells. It plays a crucial role in the process of translation, where genetic information encoded in messenger RNA (mRNA) is decoded to produce proteins. This protein is encoded by the RPS10 gene in humans.

Structure

40S ribosomal protein S10 is a conserved protein found in eukaryotic organisms. It consists of a single polypeptide chain that folds into a specific three-dimensional structure essential for its function within the ribosome. The protein interacts with other ribosomal proteins and RNA molecules to form the functional ribosomal subunit.

Function

As part of the small ribosomal subunit, 40S ribosomal protein S10 plays a critical role in the initiation of protein synthesis. It helps position the mRNA and transfer RNA (tRNA) molecules correctly within the ribosome, allowing for the accurate reading of the genetic code and the assembly of the growing polypeptide chain.

Role in Disease

Mutations in the RPS10 gene encoding 40S ribosomal protein S10 have been associated with certain genetic disorders and diseases. These mutations can disrupt the normal function of the ribosome, leading to defects in protein synthesis and potentially causing developmental abnormalities or other health issues.

References

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