4-Fluoro-5-methoxy-DMT

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A synthetic psychedelic compound


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4-Fluoro-5-methoxy-DMT (4-F-5-MeO-DMT) is a synthetic psychedelic compound belonging to the tryptamine class. It is structurally related to other psychedelic tryptamines such as 5-MeO-DMT and 4-AcO-DMT.

Chemical structure and properties

4-Fluoro-5-methoxy-DMT is a derivative of N,N-dimethyltryptamine (DMT), with a fluorine atom at the 4-position and a methoxy group at the 5-position of the indole ring. This modification alters its pharmacological properties compared to its parent compound, DMT.

Pharmacology

The pharmacological effects of 4-Fluoro-5-methoxy-DMT are not well-documented, but it is believed to act as a serotonin receptor agonist, similar to other psychedelic tryptamines. The presence of the fluorine atom may influence its binding affinity and metabolic stability.

Effects

The subjective effects of 4-Fluoro-5-methoxy-DMT are largely anecdotal and may include altered perception, visual hallucinations, and changes in mood and cognition. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.

Legal status

The legal status of 4-Fluoro-5-methoxy-DMT varies by country. In some jurisdictions, it may be classified as a controlled substance due to its structural similarity to other regulated tryptamines.

Synthesis

The synthesis of 4-Fluoro-5-methoxy-DMT involves the introduction of a fluorine atom and a methoxy group onto the indole ring of DMT. This process requires specialized knowledge in organic chemistry and access to specific reagents and equipment.

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Contributors: Prab R. Tumpati, MD