25C-NBOH

Overview

Chemical structure of 25C-NBOH

25C-NBOH is a potent serotonin receptor agonist belonging to the NBOH series of compounds. It is a derivative of the phenethylamine 2C-C, with a methoxy group replaced by a hydroxy group, and an N-benzyl substitution. This compound is primarily used in scientific research to study the effects of serotonin receptor activation.

Chemical Properties

25C-NBOH is chemically known as 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-hydroxyphenyl)methyl]ethanamine. It is a member of the phenethylamine class of compounds, which are known for their psychoactive properties. The presence of the N-benzyl group in 25C-NBOH increases its affinity for the 5-HT2A receptor, making it a valuable tool in neuropharmacological research.

Pharmacology

25C-NBOH acts as a selective agonist for the 5-HT2A receptor, which is a subtype of the serotonin receptor family. This receptor is implicated in various neurological processes, including mood regulation, perception, and cognition. The activation of 5-HT2A receptors by 25C-NBOH can lead to altered sensory perception and has been used to model the effects of psychedelic substances in laboratory settings.

Research Applications

Another view of the 25C-NBOH structure

25C-NBOH is utilized in research to explore the role of serotonin receptors in the brain. It is particularly useful in studies investigating the mechanisms of action of psychedelic drugs and their potential therapeutic applications. Researchers use 25C-NBOH to understand how activation of the 5-HT2A receptor can influence neural circuits and behavior.

Safety and Legal Status

As a research chemical, 25C-NBOH is not approved for human consumption and is typically handled in controlled laboratory environments. Its legal status varies by country, with some jurisdictions classifying it as a controlled substance due to its structural similarity to other psychoactive compounds.

Related Compounds

• 2C-C
• 25I-NBOH
• 25B-NBOH
• 25C-NBOMe

See Also

• Serotonin receptor
• Psychedelic research
• Neuropharmacology

Related pages

• List of psychedelic substances
• Serotonin receptor agonists