1P-BOL-148

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A psychedelic compound related to LSD


1P-BOL-148 is a synthetic psychedelic compound that is structurally related to lysergic acid diethylamide (LSD). It belongs to a class of compounds known as lysergamides, which are known for their potent effects on the human central nervous system.

Chemical Structure and Properties

Chemical structure of 1P-BOL-148

1P-BOL-148 is a derivative of the compound BOL-148, also known as 2-bromo-LSD. The "1P" prefix indicates the presence of a propionyl group attached to the nitrogen atom of the indole ring. This modification is similar to other 1P-lysergamides, such as 1P-LSD, which have been developed to explore the structure-activity relationships of these compounds.

The chemical formula of 1P-BOL-148 is C22H27BrN2O2, and it has a molecular weight of 431.37 g/mol. The presence of the bromine atom in the structure is a key feature that distinguishes it from other lysergamides.

Pharmacology

1P-BOL-148 is believed to act as a partial agonist at the 5-HT2A receptor, which is the primary target for classical psychedelics. The interaction with this receptor is thought to be responsible for the psychedelic effects experienced by users. However, detailed pharmacological studies on 1P-BOL-148 are limited, and its exact mechanism of action remains to be fully elucidated.

Effects

The effects of 1P-BOL-148 are reported to be similar to those of other lysergamides, such as LSD. Users may experience alterations in perception, mood, and cognition. Common effects include visual hallucinations, changes in thought patterns, and an altered sense of time. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.

Legal Status

The legal status of 1P-BOL-148 varies by country. In some jurisdictions, it may be considered a controlled substance due to its structural similarity to LSD. In others, it may be legal or exist in a legal gray area. It is important for individuals to be aware of the laws in their region before possessing or using this compound.

Related Compounds

1P-BOL-148 is part of a broader family of lysergamides, which includes:

These compounds share a common core structure but differ in their side chains, which can significantly affect their pharmacological properties and subjective effects.

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Contributors: Prab R. Tumpati, MD