Α,N,N,O-TMS
Α,N,N,O-TMS is a chemical compound that belongs to the class of tryptamines, which are structurally related to the neurotransmitter serotonin. This compound is of interest in the field of psychopharmacology due to its structural similarity to other psychoactive substances.
Chemical Structure
Α,N,N,O-TMS is a derivative of the tryptamine molecule, characterized by the presence of a methoxy group at the 5-position of the indole ring, and additional methyl groups attached to the nitrogen atoms. The full chemical name is 5-methoxy-Α,N,N-trimethyltryptamine.
Synthesis
The synthesis of Α,N,N,O-TMS involves the methylation of the tryptamine core. This process typically requires the use of methylating agents and specific reaction conditions to ensure the selective addition of methyl groups to the nitrogen atoms and the oxygen atom of the methoxy group.
Pharmacology
Α,N,N,O-TMS is believed to interact with the serotonin receptors in the brain, similar to other tryptamines. However, detailed studies on its pharmacological effects and receptor binding affinities are limited. It is hypothesized to have psychoactive properties, although its potency and efficacy compared to other tryptamines like psilocybin or DMT are not well-documented.
Potential Effects
Due to its structural similarity to other psychoactive tryptamines, Α,N,N,O-TMS may produce effects such as altered perception, mood changes, and cognitive shifts. However, empirical data on its effects in humans or animals is scarce, and further research is needed to understand its potential impact on the central nervous system.
Legal Status
The legal status of Α,N,N,O-TMS varies by country. In many jurisdictions, it may be classified under analog laws that regulate substances similar to controlled tryptamines. Researchers interested in studying this compound must be aware of the legal implications and obtain necessary permissions.
Related Compounds
Α,N,N,O-TMS is related to other tryptamines such as 5-MeO-DMT, DMT, and psilocin. These compounds share a common indole structure and are known for their psychoactive properties.
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Contributors: Prab R. Tumpati, MD