Fibrofolliculoma
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| Fibrofolliculoma | |
|---|---|
| |
| Synonyms | |
| Pronounce | |
| Specialty | Dermatology |
| Symptoms | Small, dome-shaped papules on the face, neck, and upper trunk |
| Complications | |
| Onset | Usually in adulthood |
| Duration | |
| Types | |
| Causes | Genetic mutation in the FLCN gene |
| Risks | |
| Diagnosis | Clinical examination, skin biopsy |
| Differential diagnosis | Trichodiscoma, Angiofibroma, Basal cell carcinoma |
| Prevention | |
| Treatment | Laser therapy, Surgical excision |
| Medication | |
| Prognosis | Generally benign |
| Frequency | Rare |
| Deaths | |
Fibrofolliculoma is a benign skin lesion that is associated with Birt-Hogg-Dubé syndrome. It is characterized by a proliferation of fibrous tissue around a hair follicle.
Clinical Presentation[edit]
Fibrofolliculomas typically present as small, skin-colored papules on the face, neck, and upper trunk. They are usually asymptomatic, but can sometimes cause cosmetic concern due to their appearance.
Pathogenesis[edit]
The exact pathogenesis of fibrofolliculomas is not fully understood. However, they are known to be associated with mutations in the Folliculin gene, which is also implicated in Birt-Hogg-Dubé syndrome.
Diagnosis[edit]
Diagnosis of fibrofolliculomas is typically made based on clinical examination and confirmed with histopathological examination. The characteristic histological feature is a proliferation of fibrous tissue around a hair follicle.
Treatment[edit]
Treatment of fibrofolliculomas is usually not necessary unless they are causing cosmetic concern. In such cases, they can be removed with surgical excision or laser treatment.
Prognosis[edit]
The prognosis for fibrofolliculomas is generally good, as they are benign lesions. However, they can be a marker for Birt-Hogg-Dubé syndrome, which can have more serious implications.
See Also[edit]
References[edit]
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