Myerson's sign

Myerson's sign
Synonyms	Glabellar tap sign
Pronounce	N/A
Specialty	N/A
Symptoms	Persistent blinking when the glabella is tapped
Complications	N/A
Onset	N/A
Duration	N/A
Types	N/A
Causes	Often associated with Parkinson's disease
Risks	N/A
Diagnosis	Clinical examination
Differential diagnosis	Parkinson's disease, Progressive supranuclear palsy, Wilson's disease
Prevention	N/A
Treatment	Treatment of underlying condition
Medication	N/A
Prognosis	N/A
Frequency	Common in Parkinson's disease patients
Deaths	N/A

``` This template provides a structured summary of Myerson's sign, a clinical sign observed in neurology, particularly associated with Parkinson's disease. It includes key information such as synonyms, field of study, symptoms, causes, diagnosis, differential diagnosis, treatment, and frequency. Each keyword is linked to its respective Wikipedia page for further reading. Myerson's sign is a neurological symptom where a patient is unable to resist blinking when tapped on the bridge of the nose. This sign is often associated with Parkinson's disease and other extrapyramidal disorders.

Overview

Myerson's sign is a clinical sign in which repetitive tapping (about 2 per second) over the bridge of the nose produces a sustained blink response (glabellar tap reflex). The sign is named after the American neurologist Abraham Myerson. It is often associated with Parkinson's disease and is considered a form of hypokinesia.

Clinical significance

Myerson's sign is often used as a diagnostic tool in the evaluation of patients with suspected Parkinson's disease. It is one of the motor symptoms that may be present in the early stages of the disease. However, it is not specific to Parkinson's disease and can also be seen in other conditions such as progressive supranuclear palsy, Wilson's disease, and Huntington's disease.

Pathophysiology

The exact mechanism of Myerson's sign is not fully understood. It is thought to be due to a loss of inhibition in the brainstem reflexes, which is a characteristic feature of Parkinson's disease and other extrapyramidal disorders. The sustained blink response is believed to be due to a failure of the normal inhibitory processes in the brain that control the blink reflex.

Treatment

There is no specific treatment for Myerson's sign. Treatment is directed towards the underlying condition causing the sign. In the case of Parkinson's disease, medications such as levodopa and dopamine agonists may help to reduce the severity of the sign.

See also

• Parkinson's disease
• Extrapyramidal symptoms
• Neurological examination

References

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