Amlodipine/celecoxib

Amlodipine/celecoxib is a combination medication used in the treatment of hypertension (high blood pressure) and osteoarthritis pain. It contains two active ingredients: amlodipine, a calcium channel blocker, and celecoxib, a nonsteroidal anti-inflammatory drug (NSAID).

Etymology

The name "amlodipine" is derived from the components of the chemical name: am (amide), lo (long-acting), dipine (dihydropyridine class to which the drug belongs). The name "celecoxib" is derived from the components of the chemical name: cel (celecoxib), cox (cyclooxygenase, the enzyme inhibited by the drug), ib (inhibitor).

Pharmacology

Amlodipine works by relaxing the blood vessels, allowing blood to flow more easily, thereby lowering blood pressure. Celecoxib works by reducing hormones that cause inflammation and pain in the body.

Indications

Amlodipine/celecoxib is indicated for the treatment of hypertension and to manage the signs and symptoms of osteoarthritis.

Side Effects

Common side effects of amlodipine/celecoxib include swelling, dizziness, and stomach upset. Serious side effects may include kidney problems, heart attack, stroke, and stomach or intestinal bleeding.

Contraindications

Amlodipine/celecoxib is contraindicated in patients with known hypersensitivity to amlodipine, celecoxib, or any other component of the product. It is also contraindicated in patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

Related Terms

• Hypertension
• Osteoarthritis
• Calcium channel blocker
• Nonsteroidal anti-inflammatory drug
• Pharmacology
• Contraindication

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