Sodium aurothiomalate

Sodium aurothiomalate (also known as gold sodium thiomalate and Myochrysine) is a gold compound that is used for its anti-inflammatory and immunomodulatory effects. It is most commonly used in the treatment of rheumatoid arthritis.

History

Sodium aurothiomalate was first used in the treatment of rheumatoid arthritis in the 1930s. It was one of the first disease-modifying antirheumatic drugs (DMARDs) to be used for this purpose. The use of gold compounds in medicine, known as chrysotherapy, dates back to ancient times.

Pharmacology

Sodium aurothiomalate is administered by intramuscular injection. It is believed to work by inhibiting the activity of certain immune cells that contribute to the inflammation and joint damage seen in rheumatoid arthritis. However, the exact mechanism of action is not fully understood.

Side effects

Common side effects of sodium aurothiomalate include skin rashes, mouth ulcers, and kidney problems. Less common but more serious side effects can include blood disorders and severe allergic reactions.

See also

• Gold salts
• Rheumatoid arthritis
• Disease-modifying antirheumatic drugs

References

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  Sodium aurothiomalate